• The Lab is open

750 5th Avenue, San Diego, CA 92101

Opening hours: Mon-Thu: 3pm-midnight, Fri: 3pm-2am, Sat: 9am-2am, Sun: 9am-midnight

Be a catalyst for fun. Book your holiday party today or call our event coordinator Billy Boston 619 717 1251

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Menu

Menu

When it comes to dinner in San Diego, Zymology 21 is the most innovative new restaurant in the Gaslamp District! Inspired by the science of fermentation, Zymology 21 takes an inventive approach to the art of fine dining and craft cocktails. Chef Leyla Javadov, who made waves with her delectable menu at Café 21, and mixologist Louis Chavez have designed a menu that pushes the boundaries of gastronomy, exploring the possibilities of farm to table ingredients on a molecular level.

Events

Events

Our one of a kind food and cocktail menus bring excitement and wonder to any holiday party or event. Classic comfort foods are deliciously reimagined, cocktails are elevated to enchanting scientific concoctions served in test tubes, beakers, or even frozen, and you’re invited to experience all the magic in one of the best cocktail bars San Diego has to offer. Whether its brunch, lunch, dinner, or a cocktail you’re after, we’re all about finding exciting new ways to please your palate and broaden your mind.

Gallery

Gallery

Zymology 21 is by far the most fascinating restaurant in downtown San Diego. Don’t take our word for it though. See all of Chef Leyla Javadov and Mixologist Louis Chavez’s delightful creations in our gallery of images. These mouthwatering photos will leave you no choice but to check out for yourself one of the most intriguing new restaurants in San Diego. Are you ready to experiment?